Department of Pathology

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Comparative Pathology Laboratory

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« Services

Available Services

List of services [pdf]
Immunohistochemical stains for infectious agents [pdf]
Immunohistochemical stains for tumor markers [pdf]
Histochemical special stains [pdf]
Clinical pathology tests [pdf]
Normal rat, mouse, and dog tissues available [pdf]

News

The Comparative Pathology Laboratory recently formed a working collaboration with the Transgenic Mouse & Gene Targeting Core at Emory University.Within this reciprocal partnership, the Transgenic Mouse & Gene Targeting Core at Emory will recommend the Comparative Pathology Laboratory at UGA for phenotyping services. This recommendation is not binding; however, investigators are free to use either laboratory independently.

Laboratory Animal Pathology Services

Autopsy (Necropsy) of Research Animals
Histopathology
Immunohistochemistry
Standard Phenotyping of Genetically Engineered Mice
Clinical Pathology (Hematology, Cytology, Bone Marrow Evaluation, Urinalysis, etc.)
Imaging (Radiography, Ultrasound, MRI)
Research Collaboration and Consultation
Preparation of Letter of Collaboration and Budget for Laboratory Animal Pathology Portion of Grant Proposals
Expertise in Various Other Disciplines (Endocrinology, Neurology, Ophthalmology, Radiology, etc.) are also available through the College of Veterinary Medicine

Our Commitment to You

Timeline: 7-21 business days for routine submissions
Electronic reporting of findings, evaluation, and interpretation
Publication quality digital images with caption and legend

« Why You Need Veterinary Pathology Services

Proper interpretation of morphological changes

Specialized training is required to recognize disease-associated abnormalities (lesions) in organs and tissues
Assessment, description, and interpretation of specimens (lesions) should be performed by a pathologist
Due to species differences, human vs. laboratory animal, tissues from research animals should be evaluated by a veterinary pathologist experienced in laboratory animal pathology

Expertise in animal models for specific diseases

Choosing an appropriate animal model system
Knowing the drawbacks/limitations of the chosen animal model system (especially strain-specific pathology that can interfere with morphologic evaluation)
Assistance in developing and validating new (especially genetically modified) models

Expertise in genetically engineered mice

Various mouse strain(s) used to generate mutant mice usually have a unique set of background lesions
Type of modification: transgenic, knock-out, knock-in, etc.
Construct used can present its own set of problems: tissue-specificity of a given promoter, integration into the genome, copy number, etc.

More competitive grant applications

Assistance with appropriate sections of grant proposals

« Submission Process

Shipping address

Comparative Pathology Laboratory
Department of Pathology
501 DW Brooks Drive
Athens, GA 30602-7388

General shipping guidelines

Live research animals

Please contact us to arrange shipment of live animals.

Fresh tissues

Each fresh tissue should be placed in a leak-proof plastic container (preferably a screw-top container) and maintained at refrigerator temperatures from collection to receipt at the laboratory.

Tissues for histopathological examination

Samples should be fixed in adequate amount (i.e. 10-20 times volume of fixative to volume of tissues) of 10% neutral buffered formalin prior to shipment and should be submitted in a wide-mouth, leak-proof container. Samples need not to be refrigerated.

Federal regulations

Packaging and labeling of diagnostic specimens are governed by applicable federal regulations. Packaging should be adequate as to prevent leakage or breakage as shippers may face prosecution if spillage and damage to mail, equipment, or personnel occurs during shipment (even if the material involved is not infectious or hazardous). The shipping container should be appropriately labeled (i.e., "Perishable, Biologic Specimen", etc.) on the outside.