Answer 4 | Ophthalmic Pathology

	Fig 2. The cells in the photomicrograph are neoplastic characterized by the anisocytosis, anisokaryosis and mitotic rate. The diagnosis was spindle cell sarcoma, probably fibrosarcoma

Fig 3. The neoplastic cells appear to be originating from the lens capsule epithelium.

Comment: Post-traumatic ocular sarcoma has been frequently described in cats. Most cases are fibrosarcomas and osteosarcomas and are diagnosed 2 months to 10 years after the initiated traumatic insult in which the lens has been ruptured or other wise damaged. The cell of origin of these tumors is uncertain, however, one report suggested that the cell of origin may be released lenticular epithelial cells that have undergone fibrous metaplasia. It is interesting therefore that although it could be argued that the cells in this case could be invading the lens capsule, it does appear as if they are originating from the capsule of the ruptured lens.
Selected Reference: Dubielzig RR, J Everitt, JA Shadduck, DM Albert. Clinical and morphologic features of post-traumatic ocular sarcomas in cats. Vet Pathol, 27; 62-65: 1990
Diagnosis: Post-traumatic ocular sarcoma