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Classical Swine Fever | Pathogenesis

Natural infection usually occurs through the oronasal route and the incubation period typically varies from 7 to 10 days (it is shorter in experimental infections).

The target cells for the CSF virus are endothelial cells, lymphoreticular cells, macrophages and some specific epithelial cells.

Prenatally, the virus affects organ differentiation causing malformations. In postnatal infections, lesions are related to endothelial damage and thrombosis that causes hemorrhagic diathesis.

Clinical Signs >>

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