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JULIE M. MOORE
Associate Professor

Research interests include immune responses to malaria and malaria/HIV co-infection during human preganacy, and mouse studies of the immunopathogenesis of malaria associated pregnancy loss.

RECENT PUBLICATIONS

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Lucchi, N. W. and Moore, J. M. 2006. LPS Induces Secretion of Chemokines by Human Syncytiotrophoblast Cells in a MAPK-Dependent Manner. Journal of Reproductive Immunology. In press.

Lucchi, N. W., Koopman, R., Peterson, D. S. and Moore, J. M. 2006. Plasmodium falciparum-infected red blood cells selected for binding to cultured syncytiotrophoblast bind to chondroitin sulfate A and induce tyrosine phosphorylation in the syncytiotrophoblast. Placenta, 27(4-5):384-94.

Poovassery, J. and Moore, J. M. 2006. Murine malaria infection induces fetal loss associated with accumulation of Plasmodium chabaudi AS-infected erythrocytes in the placenta. Infection and Immunity, 74(5):2839-48.

Othoro, C., Moore, J. M., Wannemuehler, K., Nahlen, B. L., Otieno, J., Slutsker, L., Lal, A. A. and Shi, Y. P. 2006. Evaluation of various methods of maternal placental blood collection for immunology studies. Clinical and Vaccine Immunology, 3(5):568-74.

Chaisavanneyakorn, S., Lucchi, N., Abramowsky, C., Othoro, C., Chaiyaroj, S.C., Shi, Y.P, Nahlen, B.L., Peterson, D.S., Moore, J.M. and Udhayakumar, V. 2005. Immunohistological characterization of macrophage migration inhibitory factor (MIF) expression in malaria-infected placenta. Infection and Immunity, 73(6):3287-93..

Ned, R. M., Moore, J. M., Chaisavaneeyakorn, S. and Udhayakumar, V. 2005. Modulation of immune responses during HIV-malaria co- infection in pregnancy. Trends in Parasitology, 21(6):284-91. Review.

Moore, J. M., Chaisavanneyakorn, S., Perkins, D. J., Otieno, J., Nahlen, B. L., Shi, Y. P. and Udhayakumar, V. 2004. Hemozoin differentially regulates proinflammatory cytokine production in human immunodeficiency virus-seropositive and -seronegative women with placental malaria. Infection and Immunity, 72(12), 7022-9.

Moore, J. M., Shi,Y. P, Othoro, C., Nahlen, B. L., Lal, A. A, and Udhayakumar, V. 2003. Comparative flow cytometric analysis of term placental intervillous and peripheral blood from immediate postpartum women in western Kenya. Placenta, 24, 779-85.

Chaisavanneyakorn, S., Moore, J. M., Mirel, L., Othoro, C., Otieno, J., Chaiyaroj, S. C., Shi, Y. P, Nahlen, B. L., Lal, A. A, and Udhayakumar, V. 2003. Levels of macrophage inflammatory protein 1 alpha (MIP-1 alpha) and MIP-1 beta in intervillous blood plasma samples from women with placental malaria and human immunodeficiency virus infection. Clinical and Diagnostic Laboratory Immunology, 10(4), 631-6.

Perkins, D. J., Moore, J. M., Otieno, J., Shi, Y. P., Nahlen, B. L., Udhayakumar, V., Lal A. A. 2003. In vivo acquisition of hemozoin by placental blood mononuclear cells suppresses PGE2, TNF-alpha, and IL-10. Biochemical and Biophysical Research Communications, 311(4), 839-46.

Chaisavanneyakorn, S., Moore, J. M., Otieno, J., Chaiyaroj, S. C., Perkins, D. J., Shi, Y. P., Nahlen, B. L., Lal, A. A., and Udhayakumar, V. 2002. Immunity to placental malaria. III. Impairment of interleukin(IL)-12, not IL-18, and interferon-inducible protein-10 responses in the placental intervillous blood of human immunodeficiency virus/malaria-coinfected women. Journal of Infectious Diseases, 185(1), 127-31.

Chaisavanneyakorn, S., Moore, J. M., Otieno, J., Chaiyaroj, S. C., Perkins, D. J., Shi, Y. P., Nahlen, B. L., Lal, A. A,, and Udhayakumar, V. 2002. Immunity to placental malaria. IV. Placental malaria is associated with up-regulation of macrophage migration inhibitory factor in intervillous blood. Journal of Infectious Diseases, 186(9), 1371-5.

Moore, J. M., Nahlen, B., Lal, A. A. and Udhayakumar, V. 2000. Immunologic memory in the placenta: A lymphocyte recirculation hypothesis. 2000. Medical Hypotheses, 54(3), 505-10.

Moore, J. M., Nahlen, B., Lal, A. A. and Udhayakumar, V. 2000. Immunity to placental malaria. II. Placental antigen-specific cytokine responses are impaired in human immunodeficiency virus-infected women. Journal of Infectious Diseases, 182(3), 960-4.


Email
julmoore@uga.edu

Office
N330C Coverdell
706-542-5789

Degrees
BS, St. Lawrence University, 1987
PhD, University of Connecticut Health Center, 1995