LESLIE P. JONES
Research Scientist

Research interests include the expression and purification of recombinant viral proteins using mammalian, insect, and bacterial systems. Purification of native viral proteins for vaccine use. Development of novel assays for biosensing of microorganisms: nanostructures (rods, particles) for in-vivo detection of microorganisms; nanoparticles as delivery platforms for antimicrobial therapeutics, vaccines, and anti-tumor agents.

RECENT PUBLICATIONS

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Shanmukh, S., Jones, L. P., Zhao, Y., Dluhy, R. and Tripp, R. Rapid and Sensitive Detection of Respiratory Virus Molecular Signatures Using Surface Enhanced Raman spectroscopy. Submitted to Nature Methods

Harcourt, J., Alvarez, R., Jones, L. P., Henderson, C., Anderson, L. J. and Tripp, R A. 2006. Respiratory syncytial virus G protein and G protein CX3C motif adversely affect CX3CR1+ T cell responses. Journal of Immunology, 176(3):1600-8.

Tripp, R. A., Haynes, L. M., Moore, D., Anderson, B., Tamin, A., Harcourt, B. H., Jones, L. P., Yilla, M., Babcock, G. J., Greenough, T., Ambrosino, D. M., Alvarez, R., Callaway, J., Cavitt, S., Kamrud, K., Alterson, H., Smith, J., Harcourt, J. L., Miao, C., Razdan, R., Comer, J. A., Rollin, P. E., Ksiazek, T. G., Sanchez, A., Rota, P. A., Bellini, W. J. and Anderson L.J. 2005. Monoclonal antibodies to SARS-associated coronavirus (SARS-CoV): identification of neutralizing and antibodies reactive to S, N, M and E viral proteins. Journal of Virological Methods, 128(1-2):21-8.

Alvarez, R., Jones, L. P., Seal, B. S., Kapczynski, D. R. and Tripp, R. A. 2004. Serological cross-reactivity of members of the Metapneumovirus genus. Virus Research, 105(1):67-73. Erratum in: Virus Research. 2005, 107(1):109.

Haynes, L. M., Jones, L. P., Barskey, A., Anderson, L. J. and Tripp, R. A. 2003. Enhanced disease and pulmonary eosinophilia associated with formalin-inactivated respiratory syncytial virus vaccination are linked to G glycoprotein CX3C-CX3CR1 interaction and expression of substance P. Journal of Virology, 77(18):9831-44.

Tripp, R. A., Dakhama, A., Jones, L. P., Barskey, A., Gelfand, E. W. and Anderson, L. J. 2003. The G glycoprotein of respiratory syncytial virus depresses respiratory rates through the CX3C motif and substance P. Journal of Virology, 77(11):6580-4.

Jones, L. P., Zheng, H. Q., Karron, R. A., Peret, T. C., Tsou, C. and Anderson, L. J. 2002. Multiplex assay for detection of strain-specific antibodies against the two variable regions of the G protein of respiratory syncytial virus. Clinical and Diagnostic Laboratory Immunology, 9(3):633-8.

Tripp, R. A., Jones, L. P., Haynes, L. M., Zheng, H., Murphy, P. M. and Anderson, L. J. 2001. CX3C chemokine mimicry by respiratory syncytial virus G glycoprotein. Nature Immunology, 2(8):732-8.

Kurt-Jones, E. A., Popova, L., Kwinn, L., Haynes, L. M., Jones, L. P., Tripp, R. A., Walsh, E. E., Freeman, M. W., Golenbock, D. T., Anderson, L. J. and Finberg, R. W. 2000. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nature Immunology, 1(5):398-401.

Email
ljones@vet.uga.edu

Degrees
MS, University of Alabama, 1993